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Isis Pharmaceuticals Reports Positive Phase 1 Data Demonstrating ISIS-APO(a) Rx Produces Significant Reductions in Lp(a) Levels

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CARLSBAD, Calif., Nov. 16, 2013 /PRNewswire/ -- Isis Pharmaceuticals, Inc. (ISIS) announced today positive results from a Phase 1 study with ISIS-APO(a)Rx. These data were presented by Dr. Sotirios Tsimikas at the Vascular Biology Working Group global chapter meeting occurring concurrently with the American Heart Association (AHA) in Dallas, Texas. These data will also be presented at the AHA on Sunday, November 17 at 3:00 p.m. Central Time in the poster session titled 'Mechanisms and Regulation of Hepatic Lipid Metabolism.' In this study, healthy volunteers treated with ISIS-APO(a)Rx achieved dose-dependent reductions of up to 95 percent in lipoprotein(a), or Lp(a), an independent risk...

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